Radical Numerics says AI-designed phages reach a patient with a resistant infection; e-consult outcomes match in-person consults in IDWeek poster

A petri dish of pale agar dotted with round colonies of a few sizes, its clear lid tilted against it.

Radical Numerics said Oct. 20 that phages designed with its Omnii-1 artificial intelligence model were given to a patient with an antibiotic-resistant bacterial infection under an authorized, physician-led compassionate-use pathway.

The company said it cannot disclose the patient's course or outcomes. At IDWeek 2026, a retrospective poster reported mortality and readmission after asynchronous infectious disease e-consults comparable to in-person consults at a 380-bed Pennsylvania hospital.

  • AI Oct 20, 2026
    Radical Numerics said Oct. 20 that it carried out what it called "the world's first clinical use of AI-designed phages," with phages designed by its Omnii-1 model given to a patient with an antibiotic-resistant bacterial infection under an authorized, physician-led compassionate-use pathway. The company said it cannot disclose the patient's clinical course or outcomes. It said the investigational therapies have not been approved by regulatory bodies for broader clinical use and that observations from a single patient cannot establish general safety or efficacy.
  • Research Oct 22, 2026
    In a retrospective study presented at IDWeek 2026, researchers compared 115 patients first evaluated through asynchronous infectious disease e-consults at a 380-bed hospital in Blair County, Pennsylvania, from April to July 2020 with 120 of 398 in-person consult patients from April to July 2019, selected at random. In-hospital mortality was 2.6% versus 5.0% and 30-day readmission 26% versus 18%; neither difference was statistically significant, and the authors called the outcomes comparable. Median overall stay was 8 days versus 6 days (P = .004), and bacteremia was diagnosed in 34% versus 20%, Infection Control Today reported.

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  1. Radical Numerics says phages designed by its AI model were given to a patient with an antibiotic-resistant infection

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